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BMCBI
2006
69views more  BMCBI 2006»
14 years 10 months ago
Retrieval with gene queries
Background: Accuracy of document retrieval from MEDLINE for gene queries is crucially important for many applications in bioinformatics. We explore five information retrieval-base...
Aditya Kumar Sehgal, Padmini Srinivasan
BMCBI
2006
180views more  BMCBI 2006»
14 years 10 months ago
Building multiclass classifiers for remote homology detection and fold recognition
Motivation Protein remote homology prediction and fold recognition are central problems in computational biology. Supervised learning algorithms based on support vector machines a...
Huzefa Rangwala, George Karypis
BMCBI
2006
137views more  BMCBI 2006»
14 years 10 months ago
Improving the accuracy of protein secondary structure prediction using structural alignment
Background: The accuracy of protein secondary structure prediction has steadily improved over the past 30 years. Now many secondary structure prediction methods routinely achieve ...
Scott Montgomerie, Shan Sundararaj, Warren J. Gall...
BMCBI
2006
128views more  BMCBI 2006»
14 years 10 months ago
New directions in biomedical text annotation: definitions, guidelines and corpus construction
Background: While biomedical text mining is emerging as an important research area, practical results have proven difficult to achieve. We believe that an important first step tow...
W. John Wilbur, Andrey Rzhetsky, Hagit Shatkay
106
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BMCBI
2006
129views more  BMCBI 2006»
14 years 10 months ago
Fast index based algorithms and software for matching position specific scoring matrices
Background: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs in nucleotide as well as amino acid sequences....
Michael Beckstette, Robert Homann, Robert Giegeric...