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89
Voted
BMCBI
2006
14 years 10 months ago
2006
Background: Expression array data are used to predict biological functions of uncharacterized genes by comparing their expression profiles to those of characterized genes. While b...
86
Voted
BMCBI
2006
14 years 10 months ago
2006
Background: In studies that use DNA arrays to assess changes in gene expression, our goal is to evaluate the statistical significance of treatments on sets of genes. Genes can be ...
BMCBI
2006
14 years 10 months ago
2006
Metabolic networks are naturally represented as directed hypergraphs in such a way that metabolites are nodes and enzyme-catalyzed reactions form (hyper)edges. The familiar operat...
82
Voted
BMCBI
2006
14 years 10 months ago
2006
Background: Structure matching plays an important part in understanding the functional role of biological structures. Bioinformatics assists in this effort by reformulating this p...
BMCBI
2006
14 years 10 months ago
2006
Background: The increasing number of known protein structures provides valuable information about pharmaceutical targets. Drug binding sites are identifiable and suitable lead com...