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BMCBI
2006
118views more  BMCBI 2006»
14 years 10 months ago
Gene Expression Profiles Distinguish the Carcinogenic Effects of Aristolochic Acid in Target (Kidney) and Non-target (Liver) Tis
Background: Aristolochic acid (AA) is the active component of herbal drugs derived from Aristolochia species that have been used for medicinal purposes since antiquity. AA, howeve...
Tao Chen, Lei Guo, Lu Zhang 0013, Leming M. Shi, H...
BMCBI
2006
85views more  BMCBI 2006»
14 years 10 months ago
SVM-based prediction of caspase substrate cleavage sites
Background: Caspases belong to a class of cysteine proteases which function as critical effectors in apoptosis and inflammation by cleaving substrates immediately after unique sit...
Lawrence J. K. Wee, Tin Wee Tan, Shoba Ranganathan
65
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BMCBI
2006
97views more  BMCBI 2006»
14 years 10 months ago
A comparative analysis of the information content in long and short SAGE libraries
Background: Serial Analysis of Gene Expression (SAGE) is a powerful tool to determine gene expression profiles. Two types of SAGE libraries, ShortSAGE and LongSAGE, are classified...
Yi-Ju Li, Puting Xu, Xuejun Qin, Donald E. Schmech...
89
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BMCBI
2006
153views more  BMCBI 2006»
14 years 10 months ago
Cancer diagnosis marker extraction for soft tissue sarcomas based on gene expression profiling data by using projective adaptive
Background: Recent advances in genome technologies have provided an excellent opportunity to determine the complete biological characteristics of neoplastic tissues, resulting in ...
Hiro Takahashi, Takeshi Nemoto, Teruhiko Yoshida, ...
69
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BMCBI
2006
132views more  BMCBI 2006»
14 years 10 months ago
Comprehensive quality control utilizing the prehybridization third-dye image leads to accurate gene expression measurements by c
Background: Gene expression profiling using microarrays has become an important genetic tool. Spotted arrays prepared in academic labs have the advantage of low cost and high desi...
Xujing Wang, Shuang Jia, Lisa Meyer, Bixia Xiang, ...