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75
Voted
BMCBI
2006
14 years 10 months ago
2006
Background: Two-dimensional gel electrophoresis (2DE) is a powerful technique to examine post-translational modifications of complexly modulated proteins. Currently, spot detectio...
78
Voted
BMCBI
2006
14 years 10 months ago
2006
Background: Simulation of DNA-microarray data serves at least three purposes: (i) optimizing the design of an intended DNA microarray experiment, (ii) comparing existing pre-proce...
79
Voted
BMCBI
2006
14 years 10 months ago
2006
Background: Methods for predicting protein function directly from amino acid sequences are useful tools in the study of uncharacterised protein families and in comparative genomic...
BMCBI
2006
14 years 10 months ago
2006
Background: Many genome projects are left unfinished due to complex, repeated regions. Finishing is the most time consuming step in sequencing and current finishing tools are not ...
86
Voted
BMCBI
2006
14 years 10 months ago
2006
Background: Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Rega...