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70
Voted
BMCBI
2007
2007
Missing channels in two-colour microarray experiments: Combining single-channel and two-channel data
14 years 10 months ago
Background: There are mechanisms, notably ozone degradation, that can damage a single channel of two-channel microarray experiments. Resulting analyses therefore often choose betw...
87
Voted
BMCBI
2007
14 years 10 months ago
2007
Background: During generation of microarray data, various forms of systematic biases are frequently introduced which limits accuracy and precision of the results. In order to prop...
BMCBI
2007
14 years 10 months ago
2007
Background: Whereas the molecular assembly of protein expression clones is readily automated and routinely accomplished in high throughput, sequence verification of these clones i...
113
Voted
BMCBI
2007
14 years 10 months ago
2007
Background: The recent increase in the use of high-throughput two-hybrid analysis has generated large quantities of data on protein interactions. Specifically, the availability of...
71
Voted
BMCBI
2007
14 years 10 months ago
2007
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...