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BMCBI
2007
94views more  BMCBI 2007»
15 years 1 months ago
Model based analysis of real-time PCR data from DNA binding dye protocols
Background: Reverse transcription followed by real-time PCR is widely used for quantification of specific mRNA, and with the use of double-stranded DNA binding dyes it is becoming...
Mariano J. Alvarez, Guillermo J. Vila-Ortiz, Maria...
BMCBI
2007
119views more  BMCBI 2007»
15 years 1 months ago
Efficacy of different protein descriptors in predicting protein functional families
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...
BMCBI
2007
200views more  BMCBI 2007»
15 years 1 months ago
BNDB - The Biochemical Network Database
Background: Technological advances in high-throughput techniques and efficient data acquisition methods have resulted in a massive amount of life science data. The data is stored ...
Jan Küntzer, Christina Backes, Torsten Blum, ...
BMCBI
2007
149views more  BMCBI 2007»
15 years 1 months ago
Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors
Background: Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivate...
Xueping Yu, Jimmy J. Lin, Donald J. Zack, Jiang Qi...
BMCBI
2007
182views more  BMCBI 2007»
15 years 1 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen