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BMCBI
2007
14 years 10 months ago
2007
Background: Extracting biological information from high-density Affymetrix arrays is a multi-step process that begins with the accurate annotation of microarray probes. Shortfalls...
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BMCBI
2007
14 years 10 months ago
2007
Background: Clustered Regularly Interspaced Palindromic Repeats (CRISPRs) are a novel type of direct repeat found in a wide range of bacteria and archaea. CRISPRs are beginning to...
BMCBI
2007
14 years 10 months ago
2007
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
BMCBI
2007
14 years 10 months ago
2007
Background: Used alone, the MAS5.0 algorithm for generating expression summaries has been criticized for high False Positive rates resulting from exaggerated variance at low inten...
BMCBI
2007
14 years 10 months ago
2007
Background: Chromatin immunoprecipitation on tiling arrays (ChIP-chip) has been widely used to investigate the DNA binding sites for a variety of proteins on a genome-wide scale. ...