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BMCBI
2006
110views more  BMCBI 2006»
14 years 10 months ago
CpGcluster: a distance-based algorithm for CpG-island detection
Background: Despite their involvement in the regulation of gene expression and their importance as genomic markers for promoter prediction, no objective standard exists for defini...
Michael Hackenberg, Christopher Previti, Pedro Lui...
BMCBI
2006
118views more  BMCBI 2006»
14 years 10 months ago
Automatic generation of gene finders for eukaryotic species
Background: The number of sequenced eukaryotic genomes is rapidly increasing. This means that over time it will be hard to keep supplying customised gene finders for each genome. ...
Kasper Munch, Anders Krogh
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BMCBI
2005
108views more  BMCBI 2005»
14 years 10 months ago
The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymer
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
François Ferron, Cécile Bussetta, H&...
BMCBI
2005
108views more  BMCBI 2005»
14 years 10 months ago
A linear memory algorithm for Baum-Welch training
Background: Baum-Welch training is an expectation-maximisation algorithm for training the emission and transition probabilities of hidden Markov models in a fully automated way. I...
István Miklós, Irmtraud M. Meyer
BMCBI
2005
121views more  BMCBI 2005»
14 years 10 months ago
Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data
Background: A critical step in processing oligonucleotide microarray data is combining the information in multiple probes to produce a single number that best captures the express...
Kerby Shedden, Wei Chen, Rork Kuick, Debashis Ghos...