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BMCBI
2005
136views more  BMCBI 2005»
14 years 10 months ago
Identification of clustered microRNAs using an ab initio prediction method
Background: MicroRNAs (miRNAs) are endogenous 21 to 23-nucleotide RNA molecules that regulate protein-coding gene expression in plants and animals via the RNA interference pathway...
Alain Sewer, Nicodème Paul, Pablo Landgraf,...
BMCBI
2005
143views more  BMCBI 2005»
14 years 10 months ago
Gene capture prediction and overlap estimation in EST sequencing from one or multiple libraries
Background: In expressed sequence tag (EST) sequencing, we are often interested in how many genes we can capture in an EST sample of a targeted size. This information provides ins...
Ji-Ping Z. Wang, Bruce G. Lindsay 0002, Liying Cui...
BMCBI
2006
72views more  BMCBI 2006»
14 years 10 months ago
Selecting effective siRNA sequences by using radial basis function network and decision tree learning
Background: Although short interfering RNA (siRNA) has been widely used for studying gene functions in mammalian cells, its gene silencing efficacy varies markedly and there are o...
Shigeru Takasaki, Yoshihiro Kawamura, Akihiko Kona...
BMCBI
2008
85views more  BMCBI 2008»
14 years 10 months ago
Normalizing biomedical terms by minimizing ambiguity and variability
Background: One of the difficulties in mapping biomedical named entities, e.g. genes, proteins, chemicals and diseases, to their concept identifiers stems from the potential varia...
Yoshimasa Tsuruoka, John McNaught, Sophia Ananiado...
BMCBI
2008
139views more  BMCBI 2008»
14 years 10 months ago
New challenges for text mining: mapping between text and manually curated pathways
Background: Associating literature with pathways poses new challenges to the Text Mining (TM) community. There are three main challenges to this task: (1) the identification of th...
Kanae Oda, Jin-Dong Kim, Tomoko Ohta, Daisuke Okan...