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BMCBI
2008
14 years 10 months ago
2008
Background: Recent progresses in genotyping technologies allow the generation high-density genetic maps using hundreds of thousands of genetic markers for each DNA sample. The ava...
90
Voted
BMCBI
2007
14 years 10 months ago
2007
Background: Microarray technologies have evolved rapidly, enabling biologists to quantify genome-wide levels of gene expression, alternative splicing, and sequence variations for ...
89
Voted
BMCBI
2007
14 years 10 months ago
2007
Background: Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur frequent...
BMCBI
2007
14 years 10 months ago
2007
Background: The Affymetrix GeneChip technology uses multiple probes per gene to measure its expression level. Individual probe signals can vary widely, which hampers proper interp...
116
Voted
BMCBI
2007
14 years 10 months ago
2007
Background: MicroRNAs (miRNAs) are recognized as one of the most important families of noncoding RNAs that serve as important sequence-specific post-transcriptional regulators of ...