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74
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BMCBI
2008
86views more  BMCBI 2008»
14 years 10 months ago
Predicting protein linkages in bacteria: Which method is best depends on task
Background: Applications of computational methods for predicting protein functional linkages are increasing. In recent years, several bacteria-specific methods for predicting link...
Anis Karimpour-Fard, Sonia M. Leach, Ryan T. Gill,...
BMCBI
2008
99views more  BMCBI 2008»
14 years 10 months ago
Binning sequences using very sparse labels within a metagenome
Background: In metagenomic studies, a process called binning is necessary to assign contigs that belong to multiple species to their respective phylogenetic groups. Most of the cu...
Chon-Kit Kenneth Chan, Arthur L. Hsu, Saman K. Hal...
84
Voted
BMCBI
2008
81views more  BMCBI 2008»
14 years 10 months ago
A perspective for biomedical data integration: Design of databases for flow cytometry
Background: The integration of biomedical information is essential for tackling medical problems. We describe a data model in the domain of flow cytometry (FC) allowing for massiv...
John Drakos, Marina Karakantza, Nicholas C. Zoumbo...
BMCBI
2008
94views more  BMCBI 2008»
14 years 10 months ago
Conserved co-expression for candidate disease gene prioritization
Background: Genes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between gen...
Martin Oti, Jeroen van Reeuwijk, Martijn A. Huynen...
83
Voted
BMCBI
2008
145views more  BMCBI 2008»
14 years 10 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...