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BMCBI
2010
82views more  BMCBI 2010»
14 years 10 months ago
Predicting the network of substrate-enzyme-product triads by combining compound similarity and functional domain composition
Background: Metabolic pathway is a highly regulated network consisting of many metabolic reactions involving substrates, enzymes, and products, where substrates can be transformed...
Lei Chen, Kai-Yan Feng, Yu-Dong Cai, Kuo-Chen Chou...
BMCBI
2010
145views more  BMCBI 2010»
14 years 10 months ago
WaveletQuant, an improved quantification software based on wavelet signal threshold de-noising for labeled quantitative proteomi
Background: Quantitative proteomics technologies have been developed to comprehensively identify and quantify proteins in two or more complex samples. Quantitative proteomics base...
Fan Mo, Qun Mo, Yuanyuan Chen, David R. Goodlett, ...
BMCBI
2010
118views more  BMCBI 2010»
14 years 10 months ago
Bacillus anthracis genome organization in light of whole transcriptome sequencing
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...
Jeffrey Martin, Wenhan Zhu, Karla D. Passalacqua, ...
BMCBI
2010
208views more  BMCBI 2010»
14 years 10 months ago
A multi-filter enhanced genetic ensemble system for gene selection and sample classification of microarray data
Background: Feature selection techniques are critical to the analysis of high dimensional datasets. This is especially true in gene selection from microarray data which are common...
Pengyi Yang, Bing Bing Zhou, Zili Zhang, Albert Y....
BMCBI
2010
95views more  BMCBI 2010»
14 years 10 months ago
Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
Background: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs m...
Can Yang, Xiang Wan, Qiang Yang, Hong Xue, Weichua...