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BMCBI
2010
14 years 10 months ago
2010
Background: Genome-wide association studies have been successful in finding common variants influencing common traits. However, these associations only account for a fraction of t...
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BMCBI
2010
14 years 10 months ago
2010
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
BMCBI
2010
14 years 10 months ago
2010
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
BMCBI
2010
14 years 10 months ago
2010
Background: It has now become clear that gene-gene interactions and gene-environment interactions are ubiquitous and fundamental mechanisms for the development of complex diseases...
BMCBI
2010
14 years 10 months ago
2010
Background: Accurate prediction of antigenic epitopes is important for immunologic research and medical applications, but it is still an open problem in bioinformatics. The case f...