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94
Voted
BMCBI
2010
14 years 10 months ago
2010
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
91
Voted
BMCBI
2010
14 years 10 months ago
2010
Background: Mass spectrometry (MS) is an essential analytical tool in proteomics. Many existing algorithms for peptide detection are based on isotope template matching and usually...
BMCBI
2010
14 years 10 months ago
2010
Background: Microarray experiments have become very popular in life science research. However, if such experiments are only considered independently, the possibilities for analysi...
76
Voted
BMCBI
2010
14 years 10 months ago
2010
Background: The enormous throughput and low cost of second-generation sequencing platforms now allow research and clinical geneticists to routinely perform single experiments that...
64
Voted
BMCBI
2010
14 years 10 months ago
2010
Background: Recent advances in antibody microarray technology have made it possible to measure the expression of hundreds of proteins simultaneously in a competitive dual-colour a...