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BMCBI
2010
102views more  BMCBI 2010»
14 years 10 months ago
Peptide binding predictions for HLA DR, DP and DQ molecules
Background: MHC class II binding predictions are widely used to identify epitope candidates in infectious agents, allergens, cancer and autoantigens. The vast majority of predicti...
Peng Wang, John Sidney, Yohan Kim, Alessandro Sett...
BMCBI
2010
86views more  BMCBI 2010»
14 years 10 months ago
The oligodeoxynucleotide sequences corresponding to never-expressed peptide motifs are mainly located in the non-coding strand
Background: We study the usage of specific peptide platforms in protein composition. Using the pentapeptide as a unit of length, we find that in the universal proteome many pentap...
Giovanni Capone, Giuseppe Novello, Candida Fasano,...
BMCBI
2010
164views more  BMCBI 2010»
14 years 7 months ago
Merged consensus clustering to assess and improve class discovery with microarray data
Background: One of the most commonly performed tasks when analysing high throughput gene expression data is to use clustering methods to classify the data into groups. There are a...
T. Ian Simpson, J. Douglas Armstrong, Andrew P. Ja...
BMCBI
2010
196views more  BMCBI 2010»
14 years 7 months ago
Content-based microarray search using differential expression profiles
Background: With the expansion of public repositories such as the Gene Expression Omnibus (GEO), we are rapidly cataloging cellular transcriptional responses to diverse experiment...
Jesse M. Engreitz, Alexander A. Morgan, Joel Dudle...
BMCBI
2010
126views more  BMCBI 2010»
14 years 7 months ago
Systematic integration of experimental data and models in systems biology
Background: The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction ...
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Sp...