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BMCBI
2010
201views more  BMCBI 2010»
14 years 7 months ago
IntelliGO: a new vector-based semantic similarity measure including annotation origin
Background: The Gene Ontology (GO) is a well known controlled vocabulary describing the biological process, molecular function and cellular component aspects of gene annotation. I...
Sidahmed Benabderrahmane, Malika Smaïl-Tabbon...
BMCBI
2010
133views more  BMCBI 2010»
14 years 7 months ago
Initial steps towards a production platform for DNA sequence analysis on the grid
Background: Bioinformatics is confronted with a new data explosion due to the availability of high throughput DNA sequencers. Data storage and analysis becomes a problem on local ...
Angela C. M. Luyf, Barbera D. C. van Schaik, Miche...
BMCBI
2010
259views more  BMCBI 2010»
14 years 5 months ago
Rule-based spatial modeling with diffusing, geometrically constrained molecules
Background: We suggest a new type of modeling approach for the coarse grained, particle-based spatial simulation of combinatorially complex chemical reaction systems. In our appro...
Gerd Gruenert, Bashar Ibrahim, Thorsten Lenser, Ma...
BMCBI
2010
117views more  BMCBI 2010»
14 years 5 months ago
Screensaver: an open source lab information management system (LIMS) for high throughput screening facilities
Background: Shared-usage high throughput screening (HTS) facilities are becoming more common in academe as large-scale small molecule and genome-scale RNAi screening strategies ar...
Andrew N. Tolopko, John P. Sullivan, Sean D. Erick...
BMCBI
2010
148views more  BMCBI 2010»
14 years 5 months ago
SKPDB: a structural database of shikimate pathway enzymes
Background: The functional and structural characterisation of enzymes that belong to microbial metabolic pathways is very important for structure-based drug design. The main inter...
Helen A. Arcuri, Geraldo F. D. Zafalon, Evandro A....