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BMCBI
2010
66views more  BMCBI 2010»
14 years 10 months ago
BALL - biochemical algorithms library 1.3
Andreas Hildebrandt, Anna Katharina Dehof, Alexand...
BMCBI
2010
91views more  BMCBI 2010»
14 years 10 months ago
Coverage statistics for sequence census methods
We study the shape of coverage functions resulting from the sequencing of random genome fragments, and show that they can be described by Galton-Watson trees. This extends standar...
Steven N. Evans, Valerie Hower, Lior Pachter
BMCBI
2010
101views more  BMCBI 2010»
14 years 10 months ago
Optimizing structural modeling for a specific protein scaffold: knottins or inhibitor cystine knots
Background: Knottins are small, diverse and stable proteins with important drug design potential. They can be classified in 30 families which cover a wide range of sequences (1621...
Jérôme Gracy, Laurent Chiche
BMCBI
2010
124views more  BMCBI 2010»
14 years 10 months ago
The value of position-specific priors in motif discovery using MEME
Background: Position-specific priors have been shown to be a flexible and elegant way to extend the power of Gibbs sampler-based motif discovery algorithms. Information of many ty...
Timothy L. Bailey, Mikael Bodén, Tom Whitin...
BMCBI
2010
125views more  BMCBI 2010»
14 years 10 months ago
Active machine learning for transmembrane helix prediction
Background: About 30% of genes code for membrane proteins, which are involved in a wide variety of crucial biological functions. Despite their importance, experimentally determine...
Hatice U. Osmanbeyoglu, Jessica A. Wehner, Jaime G...