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BMCBI
2010
133views more  BMCBI 2010»
14 years 10 months ago
Data analysis issues for allele-specific expression using Illumina's GoldenGate assay
Background: High-throughput measurement of allele-specific expression (ASE) is a relatively new and exciting application area for array-based technologies. In this paper, we explo...
Matthew E. Ritchie, Matthew S. Forrest, Antigone S...
BMCBI
2010
88views more  BMCBI 2010»
14 years 10 months ago
MetaBar - a tool for consistent contextual data acquisition and standards compliant submission
Background: Environmental sequence datasets are increasing at an exponential rate; however, the vast majority of them lack appropriate descriptors like sampling location, time and...
Wolfgang Hankeln, Pier Luigi Buttigieg, Dennis Fin...
BMCBI
2010
96views more  BMCBI 2010»
14 years 10 months ago
FluTyper-an algorithm for automated typing and subtyping of the influenza virus from high resolution mass spectral data
Background: High resolution mass spectrometry has been employed to rapidly and accurately type and subtype influenza viruses. The detection of signature peptides with unique theor...
Jason W. H. Wong, Alexander B. Schwahn, Kevin M. D...
BMCBI
2010
109views more  BMCBI 2010»
14 years 10 months ago
FPGA acceleration of the phylogenetic likelihood function for Bayesian MCMC inference methods
Background: Likelihood (ML)-based phylogenetic inference has become a popular method for estimating the evolutionary relationships among species based on genomic sequence data. Th...
Stephanie Zierke, Jason D. Bakos
BMCBI
2010
124views more  BMCBI 2010»
14 years 10 months ago
A Dynamic Noise Level Algorithm for Spectral Screening of Peptide MS/MS Spectra
Background: High-throughput shotgun proteomics data contain a significant number of spectra from non-peptide ions or spectra of too poor quality to obtain highly confident peptide...
Hua Xu, Michael A. Freitas