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BMCBI
2010
62views more  BMCBI 2010»
14 years 10 months ago
Forward-time simulation of realistic samples for genome-wide association studies
Background: Forward-time simulations have unique advantages in power and flexibility for the simulation of genetic samples of complex human diseases because they can closely mimic...
Bo Peng, Christopher I. Amos
BMCBI
2010
132views more  BMCBI 2010»
14 years 10 months ago
An interaction-motif-based scoring function for protein-ligand docking
Background: A good scoring function is essential for molecular docking computations. In conventional scoring functions, energy terms modeling pairwise interactions are cumulativel...
Zhong-Ru Xie, Ming-Jing Hwang
BMCBI
2010
126views more  BMCBI 2010»
14 years 10 months ago
Simulation of a Petri net-based Model of the Terpenoid Biosynthesis Pathway
Background: The development and simulation of dynamic models of terpenoid biosynthesis has yielded a systems perspective that provides new insights into how the structure of this ...
Aliah Hazmah Hawari, Zeti-Azura Mohamed-Hussein
BMCBI
2010
95views more  BMCBI 2010»
14 years 10 months ago
Protein structure modelling and evaluation based on a 4-distance description of side-chain interactions
Background: Accurate evaluation and modelling of residue-residue interactions within and between proteins is a key aspect of computational structure prediction including homology ...
Vladimir Potapov, Mati Cohen, Yuval Inbar, Gideon ...
BMCBI
2010
164views more  BMCBI 2010»
14 years 10 months ago
Gene regulatory networks modelling using a dynamic evolutionary hybrid
Background: Inference of gene regulatory networks is a key goal in the quest for understanding fundamental cellular processes and revealing underlying relations among genes. With ...
Ioannis A. Maraziotis, Andrei Dragomir, Dimitris T...