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BMCBI
2010
107views more  BMCBI 2010»
14 years 5 months ago
Interaction prediction and classification of PDZ domains
Background: PDZ domain is a well-conserved, structural protein domain found in hundreds of signaling proteins that are otherwise unrelated. PDZ domains can bind to the C-terminal ...
Sibel Kalyoncu, Ozlem Keskin, Attila Gürsoy
BMCBI
2010
93views more  BMCBI 2010»
14 years 10 months ago
JunctionViewer: customizable annotation software for repeat-rich genomic regions
Background: Repeat-rich regions such as centromeres receive less attention than their gene-rich euchromatic counterparts because the former are difficult to assemble and analyze. ...
Thomas K. Wolfgruber, Gernot G. Presting
BMCBI
2010
166views more  BMCBI 2010»
14 years 10 months ago
Accurate peak list extraction from proteomic mass spectra for identification and profiling studies
Background: Mass spectrometry is an essential technique in proteomics both to identify the proteins of a biological sample and to compare proteomic profiles of different samples. ...
Nicola Barbarini, Paolo Magni
BMCBI
2010
120views more  BMCBI 2010»
14 years 10 months ago
Optimal contact definition for reconstruction of Contact Maps
Background: Contact maps have been extensively used as a simplified representation of protein structures. They capture most important features of a protein's fold, being pref...
Jose M. Duarte, Rajagopal Sathyapriya, Henning Ste...
BMCBI
2010
97views more  BMCBI 2010»
14 years 10 months ago
Incorporating significant amino acid pairs to identify O-linked glycosylation sites on transmembrane proteins and non-transmembr
Background: While occurring enzymatically in biological systems, O-linked glycosylation affects protein folding, localization and trafficking, protein solubility, antigenicity, bi...
Shu-An Chen, Tzong-Yi Lee, Yu-Yen Ou