Sciweavers

676 search results - page 20 / 136
» bmcbi 2010
Sort
View
BMCBI
2010
123views more  BMCBI 2010»
14 years 10 months ago
Computationally efficient flux variability analysis
Background: Flux variability analysis is often used to determine robustness of metabolic models in various simulation conditions. However, its use has been somehow limited by the ...
Steinn Gudmundsson, Ines Thiele
72
Voted
BMCBI
2010
141views more  BMCBI 2010»
14 years 10 months ago
Genome scale prediction of substrate specificity for acyl adenylate superfamily of enzymes based on active site residue profiles
Background: Enzymes belonging to acyl:CoA synthetase (ACS) superfamily activate wide variety of substrates and play major role in increasing the structural and functional diversit...
Pankaj Khurana, Rajesh S. Gokhale, Debasisa Mohant...
BMCBI
2010
119views more  BMCBI 2010»
14 years 10 months ago
Functional classification of proteins based on projection of amino acid sequences: application for prediction of protein kinase
Background: The knowledge about proteins with specific interaction capacity to the protein partners is very important for the modeling of cell signaling networks. However, the exp...
Boris Sobolev, Dmitry Filimonov, Alexey Lagunin, A...
BMCBI
2010
99views more  BMCBI 2010»
14 years 10 months ago
Assignment of chromosomal locations for unassigned SNPs/scaffolds based on pair-wise linkage disequilibrium estimates
Background: Recent developments of high-density SNP chips across a number of species require accurate genetic maps. Despite rapid advances in genome sequence assembly and availabi...
Mehar S. Khatkar, Matthew Hobbs, Markus Neuditschk...
BMCBI
2010
139views more  BMCBI 2010»
14 years 10 months ago
MOTIPS: Automated Motif Analysis for Predicting Targets of Modular Protein Domains
Background: Many protein interactions, especially those involved in signaling, involve short linear motifs consisting of 5-10 amino acid residues that interact with modular protei...
Hugo Y. K. Lam, Philip M. Kim, Janine Mok, Raffi T...