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BMCBI
2010
115views more  BMCBI 2010»
14 years 10 months ago
Non-coding RNA detection methods combined to improve usability, reproducibility and precision
Background: Non-coding RNAs gain more attention as their diverse roles in many cellular processes are discovered. At the same time, the need for efficient computational prediction...
Peter Raasch, Ulf Schmitz, Nadja Patenge, Julio Ve...
BMCBI
2010
116views more  BMCBI 2010»
14 years 10 months ago
Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences
Background: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the eff...
Jeffry D. Sander, Deepak Reyon, Morgan L. Maeder, ...
BMCBI
2010
69views more  BMCBI 2010»
14 years 10 months ago
Reanalyze unassigned reads in Sanger based metagenomic data using conserved gene adjacency
Background: Investigation of metagenomes provides greater insight into uncultured microbial communities. The improvement in sequencing technology, which yields a large amount of s...
Francis C. Weng, Chien-Hao Su, Ming-Tsung Hsu, Tse...
BMCBI
2010
150views more  BMCBI 2010»
14 years 7 months ago
Kernel based methods for accelerated failure time model with ultra-high dimensional data
Background: Most genomic data have ultra-high dimensions with more than 10,000 genes (probes). Regularization methods with L1 and Lp penalty have been extensively studied in survi...
Zhenqiu Liu, Dechang Chen, Ming Tan, Feng Jiang, R...
BMCBI
2010
150views more  BMCBI 2010»
14 years 9 months ago
DeltaProt: a software toolbox for comparative genomics
Background: Statistical bioinformatics is the study of biological data sets obtained by new micro-technologies by means of proper statistical methods. For a better understanding o...
Steinar Thorvaldsen, Tor Flå, Nils Willassen