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» c-GAMMA: Comparative Genome Analysis of Molecular Markers
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BMCBI
2004
151views more  BMCBI 2004»
14 years 9 months ago
A computational approach for ordering signal transduction pathway components from genomics and proteomics Data
Background: Signal transduction is one of the most important biological processes by which cells convert an external signal into a response. Novel computational approaches to mapp...
Yin Liu, Hongyu Zhao
BMCBI
2008
131views more  BMCBI 2008»
14 years 9 months ago
Major copy proportion analysis of tumor samples using SNP arrays
Background: Single nucleotide polymorphisms (SNPs) are the most common genetic variations in the human genome and are useful as genomic markers. Oligonucleotide SNP microarrays ha...
Cheng Li, Rameen Beroukhim, Barbara A. Weir, Wendy...
WOB
2004
14 years 10 months ago
Mutual Information Content of Homologous DNA Sequences
The necessary information to reproduce and keep an organism is codified in acid nucleic molecules. Deepening the knowledge about how the information is stored in these bio-sequence...
Luciana Pessoa, Helena Cristina da Gama Leit&atild...
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BMCBI
2004
131views more  BMCBI 2004»
14 years 9 months ago
Detection of chromosomal regions showing differential gene expression in human skeletal muscle and in alveolar rhabdomyosarcoma
Background: Rhabdomyosarcoma is a relatively common tumour of the soft tissue, probably due to regulatory disruption of growth and differentiation of skeletal muscle stem cells. I...
Andrea Bisognin, Stefania Bortoluzzi, Gian Antonio...
JCB
2007
94views more  JCB 2007»
14 years 9 months ago
A Quantile Method for Sizing Optical Maps
Optical mapping is an integrated system for the analysis of single DNA molecules. It constructs restriction maps (noted as “optical map”) from individual DNA molecules present...
Haifeng Li, Anton Valouev, David C. Schwartz, Mich...