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BMCBI
2005
105views more  BMCBI 2005»
14 years 11 months ago
SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management
Background: Single nucleotide polymorphisms (SNPs) provide an important tool in pinpointing susceptibility genes for complex diseases and in unveiling human molecular evolution. S...
Lin Wang, Simin Liu, Tianhua Niu, Xin Xu
BMCBI
2005
156views more  BMCBI 2005»
14 years 11 months ago
A new dynamical layout algorithm for complex biochemical reaction networks
Background: To study complex biochemical reaction networks in living cells researchers more and more rely on databases and computational methods. In order to facilitate computatio...
Katja Wegner, Ursula Kummer
BMCBI
2005
113views more  BMCBI 2005»
14 years 11 months ago
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks
Background: Biological processes are carried out by coordinated modules of interacting molecules. As clustering methods demonstrate that genes with similar expression display incr...
Cecily J. Wolfe, Isaac S. Kohane, Atul J. Butte
BMCBI
2005
147views more  BMCBI 2005»
14 years 11 months ago
Calibration of mass spectrometric peptide mass fingerprint data without specific external or internal calibrants
Background: Peptide Mass Fingerprinting (PMF) is a widely used mass spectrometry (MS) method of analysis of proteins and peptides. It relies on the comparison between experimental...
Witold E. Wolski, Maciej Lalowski, Peter Jungblut,...
BMCBI
2005
86views more  BMCBI 2005»
14 years 11 months ago
WebArray: an online platform for microarray data analysis
Background: Many cutting-edge microarray analysis tools and algorithms, including commonly used limma and affy packages in Bioconductor, need sophisticated knowledge of mathematic...
Xiaoqin Xia, Michael McClelland, Yipeng Wang
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