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BMCBI
2005
14 years 10 months ago
2005
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
BMCBI
2005
14 years 10 months ago
2005
Background: Pathogenicity islands (PAIs), distinct genomic segments of pathogens encoding virulence factors, represent a subgroup of genomic islands (GIs) that have been acquired ...
BMCBI
2005
2005
A microarray data-based semi-kinetic method for predicting quantitative dynamics of genetic networks
14 years 10 months ago
Background: Elucidating the dynamic behaviour of genetic regulatory networks is one of the most significant challenges in systems biology. However, conventional quantitative predi...
BMCBI
2005
14 years 10 months ago
2005
Background: Quantitative knowledge of intracellular fluxes is important for a comprehensive characterization of metabolic networks and their functional operation. In contrast to d...
BMCBI
2005
14 years 10 months ago
2005
Background: Protein domains have long been an ill-defined concept in biology. They are generally described as autonomous folding units with evolutionary and functional independenc...