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103
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BMCBI
2011
14 years 7 months ago
Revision history aware repositories of computational models of biological systems
Background: Building repositories of computational models of biological systems ensures that published models are available for both education and further research, and can provid...
Andrew K. Miller, Tommy Yu, Randall Britten, Mike ...
124
Voted
BMCBI
2011
14 years 7 months ago
Worm Phenotype Ontology: integrating phenotype data within and beyond the C. elegans community
Background: Caenorhabditis elegans gene-based phenotype information dates back to the 1970’s, beginning with Sydney Brenner and the characterization of behavioral and morphologi...
Gary Schindelman, Jolene Fernandes, Carol Bastiani...
115
Voted
BMCBI
2011
14 years 7 months ago
Systematic error detection in experimental high-throughput screening
Background: High-throughput screening (HTS) is a key part of the drug discovery process during which thousands of chemical compounds are screened and their activity levels measure...
Plamen Dragiev, Robert Nadon, Vladimir Makarenkov
125
Voted
BMCBI
2011
14 years 7 months ago
Tree Pruner: An efficient tool for selecting data from a biased genetic database
Background: Large databases of genetic data are often biased in their representation. Thus, selection of genetic data with desired properties, such as evolutionary representation ...
Mohan Krishnamoorthy, Pragneshkumar Patel, Mira Di...
121
Voted
BMCBI
2011
14 years 7 months ago
Dr. PIAS: an integrative system for assessing the druggability of protein-protein interactions
Background: The amount of data on protein-protein interactions (PPIs) available in public databases and in the literature has rapidly expanded in recent years. PPI data can provid...
Nobuyoshi Sugaya, Toshio Furuya