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BMCBI
2004
120views more  BMCBI 2004»
14 years 9 months ago
An approach to large scale identification of non-obvious structural similarities between proteins
Background: A new sequence independent bioinformatics approach allowing genome-wide search for proteins with similar three dimensional structures has been developed. By utilizing ...
Artem Cherkasov, Steven J. M. Jones
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BMCBI
2004
119views more  BMCBI 2004»
14 years 9 months ago
Identification of polymorphic tandem repeats by direct comparison of genome sequence from different bacterial strains : a web-ba
Background: Polymorphic tandem repeat typing is a new generic technology which has been proved to be very efficient for bacterial pathogens such as B. anthracis, M. tuberculosis, ...
France Denoeud, Gilles Vergnaud
BMCBI
2004
122views more  BMCBI 2004»
14 years 9 months ago
A comprehensive comparison of comparative RNA structure prediction approaches
Background: An increasing number of researchers have released novel RNA structure analysis and prediction algorithms for comparative approaches to structure prediction. Yet, indep...
Paul P. Gardner, Robert Giegerich
BMCBI
2004
161views more  BMCBI 2004»
14 years 9 months ago
Three-parameter lognormal distribution ubiquitously found in cDNA microarray data and its application to parametric data treatme
Background: To cancel experimental variations, microarray data must be normalized prior to analysis. Where an appropriate model for statistical data distribution is available, a p...
Tomokazu Konishi
BMCBI
2004
96views more  BMCBI 2004»
14 years 9 months ago
Gene finding in novel genomes
Background: Computational gene prediction continues to be an important problem, especially for genomes with little experimental data. Results: I introduce the SNAP gene finder whi...
Ian Korf