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BMCBI
2005
14 years 12 months ago
2005
Background: One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be e...
BMCBI
2005
14 years 12 months ago
2005
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...
BMCBI
2005
14 years 12 months ago
2005
Background: There are currently a number of competing techniques for low-level processing of oligonucleotide array data. The choice of technique has a profound effect on subsequen...
BMCBI
2005
14 years 12 months ago
2005
Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifac...
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BMCBI
2005
2005
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
14 years 12 months ago
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...