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BMCBI
2006
15 years 13 days ago
2006
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
BMCBI
2006
15 years 13 days ago
2006
Background: Determining whether a gene is differentially expressed in two different samples remains an important statistical problem. Prior work in this area has featured the use ...
110
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BMCBI
2006
15 years 13 days ago
2006
Background: Accurate methods for extraction of meaningful patterns in high dimensional data have become increasingly important with the recent generation of data types containing ...
112
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BMCBI
2006
15 years 13 days ago
2006
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
112
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BMCBI
2006
15 years 13 days ago
2006
Background: Structural analysis of cellular interaction networks contributes to a deeper understanding of network-wide interdependencies, causal relationships, and basic functiona...