39 search results - page 6 / 8 » ccmGDB: a database for cancer cell metabolism genes |
BMCBI
2010
14 years 10 months ago
2010
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
BMCBI
2008
14 years 10 months ago
2008
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
APBC
2004
14 years 11 months ago
2004
Biopathway databases have been developed, such as KEGG and EcoCyc, that compile interaction structures of biopathways together with biological annotations. However, these biopathw...
BMCBI
2006
14 years 10 months ago
2006
Background: The biological information in genomic expression data can be understood, and computationally extracted, in the context of systems of interacting molecules. The automat...
BMCBI
2005
14 years 10 months ago
2005
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...