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87
Voted
BMCBI
2008
14 years 10 months ago
2008
Background: Translation initiation site (TIS) identification is an important aspect of the gene annotation process, requisite for the accurate delineation of protein sequences fro...
111
Voted
BMCBI
2008
14 years 10 months ago
2008
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
83
Voted
BMCBI
2008
14 years 10 months ago
2008
Background: This paper addresses key biological problems and statistical issues in the analysis of large gene expression data sets that describe systemic temporal response cascade...
86
Voted
BMCBI
2008
14 years 10 months ago
2008
Background: Depending on their specific structures, noncoding RNAs (ncRNAs) play important roles in many biological processes. Interest in developing new topological indices based...
106
Voted
BMCBI
2008
14 years 10 months ago
2008
Background: Once a new genome is sequenced, one of the important questions is to determine the presence and absence of biological pathways. Analysis of biological pathways in a ge...