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84
Voted
DAGSTUHL
2006
15 years 10 days ago
2006
Programming technologies have improved continuously during the last decades, but from an Information Systems perspective, some well-known problems associated to the design and impl...
98
Voted
BMCBI
2006
14 years 11 months ago
2006
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
85
Voted
BMCBI
2006
14 years 11 months ago
2006
Background: Bioinformatics applications are now routinely used to analyze large amounts of data. Application development often requires many cycles of optimization, compiling, and...
BMCBI
2006
14 years 11 months ago
2006
Background: Genomic tiling micro arrays have great potential for identifying previously undiscovered coding as well as non-coding transcription. To-date, however, analyses of thes...
BMCBI
2006
14 years 11 months ago
2006
Background: Statistical methods for identifying positively selected sites in protein coding regions are one of the most commonly used tools in evolutionary bioinformatics. However...