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JCB
2006
129views more  JCB 2006»
14 years 10 months ago
GenRate: A Generative Model that Reveals Novel Transcripts in Genome-Tiling Microarray Data
Genome-wide microarray designs containing millions to hundreds of millions of probes are available for a variety of mammals, including mouse and human. These genome tiling arrays ...
Brendan J. Frey, Quaid Morris, Timothy R. Hughes
JCC
2006
110views more  JCC 2006»
14 years 10 months ago
Using internal and collective variables in Monte Carlo simulations of nucleic acid structures: Chain breakage/closure algorithm
: This article describes a method for solving the geometric closure problem for simplified models of nucleic acid structures by using the constant bond lengths approximation. The r...
Heinz Sklenar, Daniel Wüstner, Remo Rohs
JIB
2006
106views more  JIB 2006»
14 years 10 months ago
A structural keystone for drug design
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...
JIB
2006
220views more  JIB 2006»
14 years 10 months ago
An assessment of machine and statistical learning approaches to inferring networks of protein-protein interactions
Protein-protein interactions (PPI) play a key role in many biological systems. Over the past few years, an explosion in availability of functional biological data obtained from hi...
Fiona Browne, Haiying Wang, Huiru Zheng, Francisco...
JMIV
2006
185views more  JMIV 2006»
14 years 10 months ago
Intrinsic Statistics on Riemannian Manifolds: Basic Tools for Geometric Measurements
In medical image analysis and high level computer vision, there is an intensive use of geometric features like orientations, lines, and geometric transformations ranging from simp...
Xavier Pennec