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147
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BMCBI
2007
15 years 4 months ago
2007
Background: The problem of protein structure prediction consists of predicting the functional or native structure of a protein given its linear sequence of amino acids. This probl...
136
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BMCBI
2007
15 years 4 months ago
2007
Background: Single nucleotide polymorphisms (SNPs) and genes that exhibit presence/absence variation have provided informative marker sets for bacterial and viral genotyping. Iden...
157
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BMCBI
2007
15 years 4 months ago
2007
Background: Gene expression microarray and other multiplex data hold promise for addressing the challenges of cellular complexity, refined diagnoses and the discovery of well-targ...
161
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BMCBI
2007
15 years 4 months ago
2007
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
134
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BMCBI
2007
15 years 4 months ago
2007
Background: Currently, there exists tens of different microbial and eukaryotic metabolic reconstructions (e.g., Escherichia coli, Saccharomyces cerevisiae, Bacillus subtilis) with...