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BMCBI
2007
15 years 4 months ago
2007
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
151
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BMCBI
2007
15 years 4 months ago
2007
Background: Technological advances in high-throughput techniques and efficient data acquisition methods have resulted in a massive amount of life science data. The data is stored ...
140
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BMCBI
2007
15 years 4 months ago
2007
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
155
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BMCBI
2007
15 years 4 months ago
2007
Background: The search for enriched features has become widely used to characterize a set of genes or proteins. A key aspect of this technique is its ability to identify correlati...
129
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BMCBI
2007
15 years 4 months ago
2007
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...