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BMCBI
2005
15 years 3 months ago
2005
Background: The Generalized Hidden Markov Model (GHMM) has proven a useful framework for the task of computational gene prediction in eukaryotic genomes, due to its flexibility an...
139
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BMCBI
2005
15 years 3 months ago
2005
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
139
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BMCBI
2005
15 years 3 months ago
2005
Background: Accurate assignment of genes to pathways is essential in order to understand the functional role of genes and to map the existing pathways in a given genome. Existing ...
132
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BMCBI
2005
15 years 3 months ago
2005
Background: Determination and quantification of nucleic acid components in a mixture is usually accomplished by microarray approaches, where the mixtures are hybridized against sp...
198
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BMCBI
2005
15 years 3 months ago
2005
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...