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BMCBI
2004
151views more  BMCBI 2004»
15 years 3 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
BMCBI
2004
156views more  BMCBI 2004»
15 years 3 months ago
GeneXplorer: an interactive web application for microarray data visualization and analysis
Background: When publishing large-scale microarray datasets, it is of great value to create supplemental websites where either the full data, or selected subsets corresponding to ...
Christian A. Rees, Janos Demeter, John C. Matese, ...
BMCBI
2004
112views more  BMCBI 2004»
15 years 3 months ago
SPOC: A widely distributed domain associated with cancer, apoptosis and transcription
Background: The Split ends (Spen) family are large proteins characterised by N-terminal RNA recognition motifs (RRMs) and a conserved SPOC (Spen paralog and ortholog C-terminal) d...
Luis Sánchez-Pulido, Ana María Rojas...
BMCBI
2004
153views more  BMCBI 2004»
15 years 3 months ago
Computational protein biomarker prediction: a case study for prostate cancer
Background: Recent technological advances in mass spectrometry pose challenges in computational mathematics and statistics to process the mass spectral data into predictive models...
Michael Wagner, Dayanand N. Naik, Alex Pothen, Sri...
BMCBI
2004
142views more  BMCBI 2004»
15 years 3 months ago
GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies
Background: Microarray and other high-throughput technologies are producing large sets of interesting genes that are difficult to analyze directly. Bioinformatics tools are needed...
Bing Zhang, Denise Schmoyer, Stefan Kirov, Jay Sno...