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132
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BMCBI
2007
162views more  BMCBI 2007»
15 years 3 months ago
Genome-wide identification of specific oligonucleotides using artificial neural network and computational genomic analysis
Background: Genome-wide identification of specific oligonucleotides (oligos) is a computationallyintensive task and is a requirement for designing microarray probes, primers, and ...
Chun-Chi Liu, Chin-Chung Lin, Ker-Chau Li, Wen-Shy...
125
Voted
BMCBI
2006
134views more  BMCBI 2006»
15 years 3 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
137
Voted
BMCBI
2006
104views more  BMCBI 2006»
15 years 3 months ago
SinicView: A visualization environment for comparisons of multiple nucleotide sequence alignment tools
Background: Deluged by the rate and complexity of completed genomic sequences, the need to align longer sequences becomes more urgent, and many more tools have thus been developed...
Arthur Chun-Chieh Shih, D. T. Lee, Laurent Lin, Ch...
154
Voted
BMCBI
2007
156views more  BMCBI 2007»
15 years 3 months ago
Predictive modeling of plant messenger RNA polyadenylation sites
Background: One of the essential processing events during pre-mRNA maturation is the posttranscriptional addition of a polyadenine [poly(A)] tail. The 3'-end poly(A) track pr...
Guoli Ji, Jianti Zheng, Yingjia Shen, Xiaohui Wu, ...
164
Voted
BMCBI
2007
217views more  BMCBI 2007»
15 years 3 months ago
OntologyWidget - a reusable, embeddable widget for easily locating ontology terms
Background: Biomedical ontologies are being widely used to annotate biological data in a computer-accessible, consistent and well-defined manner. However, due to their size and co...
Catherine Beauheim, Farrell Wymore, Michael Nitzbe...