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147
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BMCBI
2008
15 years 5 months ago
2008
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
128
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BMCBI
2008
15 years 5 months ago
2008
Background: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect s...
121
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BMCBI
2008
15 years 5 months ago
2008
Background: Although carbohydrates are the third major class of biological macromolecules, after proteins and DNA, there is neither a comprehensive database for carbohydrate struc...
138
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BMCBI
2008
15 years 5 months ago
2008
Background: Linear motifs (LMs) are abundant short regulatory sites used for modulating the functions of many eukaryotic proteins. They play important roles in post-translational ...
143
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BMCBI
2008
15 years 5 months ago
2008
Background: High-throughput methods that allow for measuring the expression of thousands of genes or proteins simultaneously have opened new avenues for studying biochemical proce...