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BMCBI
2006
118views more  BMCBI 2006»
14 years 9 months ago
Low degree metabolites explain essential reactions and enhance modularity in biological networks
Background: Recently there has been a lot of interest in identifying modules at the level of genetic and metabolic networks of organisms, as well as in identifying single genes an...
Areejit Samal, Shalini Singh, Varun Giri, Sandeep ...
76
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BMCBI
2006
131views more  BMCBI 2006»
14 years 9 months ago
The statistics of identifying differentially expressed genes in Expresso and TM4: a comparison
Background: Analysis of DNA microarray data takes as input spot intensity measurements from scanner software and returns differential expression of genes between two conditions, t...
Allan A. Sioson, Shrinivasrao P. Mane, Pinghua Li,...
97
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BMCBI
2006
201views more  BMCBI 2006»
14 years 9 months ago
Gene selection algorithms for microarray data based on least squares support vector machine
Background: In discriminant analysis of microarray data, usually a small number of samples are expressed by a large number of genes. It is not only difficult but also unnecessary ...
E. Ke Tang, Ponnuthurai N. Suganthan, Xin Yao
BMCBI
2006
108views more  BMCBI 2006»
14 years 9 months ago
RibAlign: a software tool and database for eubacterial phylogeny based on concatenated ribosomal protein subunits
Background: Until today, analysis of 16S ribosomal RNA (rRNA) sequences has been the de-facto gold standard for the assessment of phylogenetic relationships among prokaryotes. How...
Hanno Teeling, Frank Oliver Glöckner
BMCBI
2006
110views more  BMCBI 2006»
14 years 9 months ago
Bias in error estimation when using cross-validation for model selection
Background: Cross-validation (CV) is an effective method for estimating the prediction error of a classifier. Some recent articles have proposed methods for optimizing classifiers...
Sudhir Varma, Richard Simon
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