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131
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BIOINFORMATICS
2010
15 years 6 months ago
2010
Motivation: As next generation sequencing is rapidly adding new genomes, their correct placement in the taxonomy needs verification. However, the current methods for confirming cl...
168
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BMCBI
2010
15 years 6 months ago
2010
Background: Principal component analysis (PCA) has gained popularity as a method for the analysis of highdimensional genomic data. However, it is often difficult to interpret the ...
172
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BMCBI
2010
15 years 6 months ago
2010
Background: Random forests (RF) have been increasingly used in applications such as genome-wide association and microarray studies where predictor correlation is frequently observ...
150
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BMCBI
2010
15 years 6 months ago
2010
Background: It has been long well known that genes do not act alone; rather groups of genes act in consort during a biological process. Consequently, the expression levels of gene...
196
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BMCBI
2010
15 years 6 months ago
2010
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...