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BMCBI
2010
15 years 5 months ago
2010
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
121
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BMCBI
2010
15 years 5 months ago
2010
Background: Estimation of DNA duplex hybridization free energy is widely used for predicting cross-hybridizations in DNA computing and microarray experiments. A number of software...
146
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BMCBI
2010
15 years 5 months ago
2010
Background: Current imaging methods such as Magnetic Resonance Imaging (MRI), Confocal microscopy, Electron Microscopy (EM) or Selective Plane Illumination Microscopy (SPIM) yield...
149
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BMCBI
2010
15 years 5 months ago
2010
Background: High-throughput methods for detecting protein-protein interactions enable us to obtain large interaction networks, and also allow us to computationally identify the as...
169
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BMCBI
2010
15 years 5 months ago
2010
Background: Biochemical networks play an essential role in systems biology. Rapidly growing network data and e research activities call for convenient visualization tools to aid i...