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106
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BMCBI
2006
107views more  BMCBI 2006»
15 years 18 days ago
Analysis of optimal phenotypic space using elementary modes as applied to Corynebacterium glutamicum
Background: Quantification of the metabolic network of an organism offers insights into possible ways of developing mutant strain for better productivity of an extracellular metab...
Kalyan Gayen, K. V. Venkatesh
85
Voted
BMCBI
2006
84views more  BMCBI 2006»
15 years 18 days ago
Inferring topology from clustering coefficients in protein-protein interaction networks
Background: Although protein-protein interaction networks determined with high-throughput methods are incomplete, they are commonly used to infer the topology of the complete inte...
Caroline C. Friedel, Ralf Zimmer
97
Voted
BMCBI
2006
135views more  BMCBI 2006»
15 years 18 days ago
Correcting ligands, metabolites, and pathways
Background: A wide range of research areas in bioinformatics, molecular biology and medicinal chemistry require precise chemical structure information about molecules and reaction...
Martin A. Ott, Gert Vriend
119
Voted
BMCBI
2006
130views more  BMCBI 2006»
15 years 18 days ago
An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution ma
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
96
Voted
BMCBI
2006
130views more  BMCBI 2006»
15 years 17 days ago
4SALE - A tool for synchronous RNA sequence and secondary structure alignment and editing
Background: In sequence analysis the multiple alignment builds the fundament of all proceeding analyses. Errors in an alignment could strongly influence all succeeding analyses an...
Philipp N. Seibel, Tobias Müller, Thomas Dand...