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120
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BMCBI
2006
125views more  BMCBI 2006»
15 years 17 days ago
Development of an open source laboratory information management system for 2-D gel electrophoresis-based proteomics workflow
Background: In the post-genome era, most research scientists working in the field of proteomics are confronted with difficulties in management of large volumes of data, which they...
Hiraku Morisawa, Mikako Hirota, Tosifusa Toda
97
Voted
BMCBI
2007
115views more  BMCBI 2007»
15 years 16 days ago
Correlation between structure and temperature in prokaryotic metabolic networks
Background: In recent years, an extensive characterization of network structures has been made in an effort to elucidate design principles of metabolic networks, providing valuabl...
Kazuhiro Takemoto, Jose C. Nacher, Tatsuya Akutsu
113
Voted
BMCBI
2007
142views more  BMCBI 2007»
15 years 16 days ago
SABERTOOTH: protein structural alignment based on a vectorial structure representation
Background: The task of computing highly accurate structural alignments of proteins in very short computation time is still challenging. This is partly due to the complexity of pr...
Florian Teichert, Ugo Bastolla, Markus Porto
98
Voted
BMCBI
2007
107views more  BMCBI 2007»
15 years 16 days ago
Linking microarray reporters with protein functions
Background: The analysis of microarray experiments requires accurate and up-to-date functional annotation of the microarray reporters to optimize the interpretation of the biologi...
Stan Gaj, Arie van Erk, Rachel I. M. van Haaften, ...
101
Voted
BMCBI
2007
122views more  BMCBI 2007»
15 years 16 days ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...