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BMCBI
2007
99views more  BMCBI 2007»
14 years 12 months ago
Orthogonal projections to latent structures as a strategy for microarray data normalization
Background: During generation of microarray data, various forms of systematic biases are frequently introduced which limits accuracy and precision of the results. In order to prop...
Max Bylesjö, Daniel Eriksson, Andreas Sjö...
JCP
2007
108views more  JCP 2007»
14 years 11 months ago
A Genetic Algorithm Method to Assimilate Sensor Data for a Toxic Contaminant Release
— Following a toxic contaminant release, either accidental or intentional, predicting the transport and dispersion of the contaminant becomes a critical problem for Homeland Defe...
Sue Ellen Haupt, George S. Young, Christopher T. A...
NIPS
1997
15 years 1 months ago
EM Algorithms for PCA and SPCA
I present an expectation-maximization (EM) algorithm for principal component analysis (PCA). The algorithm allows a few eigenvectors and eigenvalues to be extracted from large col...
Sam T. Roweis
BMCBI
2006
82views more  BMCBI 2006»
14 years 12 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
BMCBI
2002
120views more  BMCBI 2002»
14 years 11 months ago
tacg - a grep for DNA
Background: Pattern matching is the core of bioinformatics; it is used in database searching, restriction enzyme mapping, and finding open reading frames. It is done repeatedly ov...
Harry Mangalam