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BMCBI
2007
142views more  BMCBI 2007»
14 years 12 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
BMCBI
2007
151views more  BMCBI 2007»
14 years 12 months ago
Minimus: a fast, lightweight genome assembler
Background: Genome assemblers have grown very large and complex in response to the need for algorithms to handle the challenges of large whole-genome sequencing projects. Many of ...
Daniel D. Sommer, Arthur L. Delcher, Steven L. Sal...
BMCBI
2007
113views more  BMCBI 2007»
14 years 12 months ago
In silico panning for a non-competitive peptide inhibitor
Background: Peptide ligands have tremendous therapeutic potential as efficacious drugs. Currently, more than 40 peptides are available in the market for a drug. However, since cos...
Yukiko Yagi, Kotaro Terada, Takahisa Noma, Kazunor...
CCE
2008
14 years 12 months ago
A hierarchical decision procedure for productivity innovation in large-scale petrochemical processes
Maintaining the best quality is essential for the survival of a company in a globally competitive world. Six Sigma activity has been widely accepted as one of the most efficient a...
Chonghun Han, Minjin Kim, En Sup Yoon
AEI
2006
101views more  AEI 2006»
14 years 12 months ago
Design issues for assistive robotics for the elderly
The worldwide population of elderly people is growing rapidly and in the coming decades the proportion of older people in the developed countries will change significantly. This d...
Qinggang Meng, Mark H. Lee