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BMCBI
2005
94views more  BMCBI 2005»
14 years 9 months ago
T.I.M.S: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory
Background: Single Nucleotide Polymorphism (SNP) genotyping is a major activity in biomedical research. The Taqman technology is one of the most commonly used approaches. It produ...
Stéphanie Monnier, David G. Cox, Tim Albion...
BMCBI
2005
196views more  BMCBI 2005»
14 years 9 months ago
Chemistry in Bioinformatics
Chemical information is now seen as critical for most areas of life sciences. But unlike Bioinformatics, where data is Openly available and freely re-usable, most chemical informa...
Peter Murray-Rust, John B. O. Mitchell, Henry S. R...
BMCBI
2005
98views more  BMCBI 2005»
14 years 9 months ago
The effects of normalization on the correlation structure of microarray data
Background: Stochastic dependence between gene expression levels in microarray data is of critical importance for the methods of statistical inference that resort to pooling test-...
Xing Qiu, Andrew I. Brooks, Lev Klebanov, Andrei Y...
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BMCBI
2005
97views more  BMCBI 2005»
14 years 9 months ago
Evolutionary distance estimation and fidelity of pair wise sequence alignment
Background: Evolutionary distances are a critical measure in comparative genomics and molecular evolutionary biology. A simulation study was used to examine the effect of alignmen...
Michael S. Rosenberg
BMCBI
2005
292views more  BMCBI 2005»
14 years 9 months ago
Atlas - a data warehouse for integrative bioinformatics
Background: We present a biological data warehouse called Atlas that locally stores and integrates biological sequences, molecular interactions, homology information, functional a...
Sohrab P. Shah, Yong Huang, Tao Xu, Macaire M. S. ...