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CSB
2005
IEEE
129views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Deformable Modeling for Improved Calculation of Molecular Velocities from Single-Particle Tracking
Single-particle tracking provides a powerful technique for measuring dynamic cellular processes on the level of individual molecules. Much recent work has been devoted to using si...
Peter M. Kasson, Mark M. Davis, Axel T. Brüng...
CSB
2005
IEEE
166views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Automated Validation of Polymerase Chain Reactions Using Amplicon Melting Curves
PCR, the polymerase chain reaction, is a fundamental tool of molecular biology. Quantitative PCR is the goldstandard methodology for determination of DNA copy numbers, quantitatin...
Tobias P. Mann, Richard Humbert, John A. Stamatoya...
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CSB
2005
IEEE
125views Bioinformatics» more  CSB 2005»
15 years 3 months ago
On Optimizing Distance-Based Similarity Search for Biological Databases
Similarity search leveraging distance-based index structures is increasingly being used for both multimedia and biological database applications. We consider distance-based indexi...
Rui Mao, Weijia Xu, Smriti R. Ramakrishnan, Glen N...
CSB
2005
IEEE
129views Bioinformatics» more  CSB 2005»
15 years 3 months ago
ssahaSNP A Polymorphism Detection Tool on a Whole Genome Scale
We present a software package which can detect homozygous SNPs and indels on a eukaryotic genome scale from millions of shotgun reads. Matching seeds of a few kmer words are found...
Zemin Ning, Mario Cáccamo, James C. Mulliki...
CSB
2005
IEEE
133views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Choosing SNPs Using Feature Selection
A major challenge for genomewide disease association studies is the high cost of genotyping large number of single nucleotide polymorphisms (SNP). The correlations between SNPs, h...
Tu Minh Phuong, Zhen Lin, Russ B. Altman