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BMCBI
2006
154views more  BMCBI 2006»
14 years 9 months ago
Agile methods in biomedical software development: a multi-site experience report
Background: Agile is an iterative approach to software development that relies on strong collaboration and automation to keep pace with dynamic environments. We have successfully ...
David W. Kane, Moses M. Hohman, Ethan G. Cerami, M...
BMCBI
2006
88views more  BMCBI 2006»
14 years 9 months ago
RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes
Background: RNA-dependent gene silencing is becoming a routine tool used in laboratories worldwide. One of the important remaining hurdles in the selection of the target sequence,...
Jean-François Lucier, Lucien Junior Bergero...
BMCBI
2006
87views more  BMCBI 2006»
14 years 9 months ago
Computational expression deconvolution in a complex mammalian organ
Background: Microarray expression profiling has been widely used to identify differentially expressed genes in complex cellular systems. However, while such methods can be used to...
Min Wang, Stephen R. Master, Lewis A. Chodosh
BMCBI
2007
144views more  BMCBI 2007»
14 years 9 months ago
Gene analogue finder: a GRID solution for finding functionally analogous gene products
Background: To date more than 2,1 million gene products from more than 100000 different species have been described specifying their function, the processes they are involved in a...
Angelica Tulipano, Giacinto Donvito, Flavio Licciu...
BMCBI
2007
152views more  BMCBI 2007»
14 years 9 months ago
Recodon: Coalescent simulation of coding DNA sequences with recombination, migration and demography
Background: Coalescent simulations have proven very useful in many population genetics studies. In order to arrive to meaningful conclusions, it is important that these simulation...
Miguel Arenas, David Posada