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BMCBI
2006
137views more  BMCBI 2006»
14 years 10 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
BMCBI
2006
91views more  BMCBI 2006»
14 years 10 months ago
Cheminformatics methods for novel nanopore analysis of HIV DNA termini
Background: Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This informat...
Stephen Winters-Hilt, Matthew Landry, Mark Akeson,...
JCB
2002
93views more  JCB 2002»
14 years 9 months ago
Unfolding of Microarray Data
The use of DNA microarrays for the analysis of complex biological samples is becoming a mainstream part of biomedical research. One of the most commonly used methods compares the ...
Andrew B. Goryachev, Pascale F. Macgregor, Aled M....
IAJIT
2006
109views more  IAJIT 2006»
14 years 10 months ago
Unconstraint Assignment Problem: A Molecular Computing Approach
: Deoxyribonucleic Acid or DNA-based computing is an emerging field that bridging the gap between chemistry, molecular biology, computer science, and mathematics. This research are...
Zuwairie Ibrahim, Yusei Tsuboi, Osamu Ono, Marzuki...
98
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HEURISTICS
2002
146views more  HEURISTICS 2002»
14 years 10 months ago
Hybrid Genetic Algorithm for DNA Sequencing with Errors
In the paper, a new hybrid genetic algorithm solving the DNA sequencing problem with negative and positive errors is presented. The algorithm has as its input a set of oligonucleo...
Jacek Blazewicz, Marta Kasprzak, Wojciech Kuroczyc...